Nuclear FKBPs, Fpr3 and Fpr4 affect genome-wide genes transcription


Fpr3 and Fpr4 of Saccharomyces cerevisiae are nuclear FK506-binding proteins each containing an extended acidic domain in addition to the conserved FK506-binding/peptidylprolyl isomerase (PPIase) domain. Previous studies have shown that the PPIase domain regulates histone H3 methylation, while the acidic domain facilitates histone deposition and may… (More)
DOI: 10.1007/s00438-013-0794-0

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