Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport.

@article{Hellberg2016NuclearEO,
  title={Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport.},
  author={Teresa Hellberg and Lars Passvogel and Katharina S. Schulz and Barbara G. Klupp and Thomas C Mettenleiter},
  journal={Advances in virus research},
  year={2016},
  volume={94},
  pages={81-140}
}
Herpesvirus particles mature in two different cellular compartments. While capsid assembly and packaging of the genomic linear double-stranded DNA occur in the nucleus, virion formation takes place in the cytoplasm by the addition of numerous tegument proteins as well as acquisition of the viral envelope by budding into cellular vesicles derived from the trans-Golgi network containing virally encoded glycoproteins. To gain access to the final maturation compartment, herpesvirus nucleocapsids… CONTINUE READING
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