Nuclear BAG-1 expression reflects malignant potential in colorectal carcinomas

@article{Kikuchi2002NuclearBE,
  title={Nuclear BAG-1 expression reflects malignant potential in colorectal carcinomas},
  author={Ryuichi Kikuchi and Tsuyoshi Noguchi and Shinsuke Takeno and Yukihiro Funada and Hatsuo Moriyama and Yoichiro Uchida},
  journal={British Journal of Cancer},
  year={2002},
  volume={87},
  pages={1136 - 1139}
}
BAG-1 is a recently identified Bcl-2-interacting anti-apoptotic protein. The aim of our study was to investigate the immunohistochemical staining pattern of BAG-1 protein in patients with colorectal cancer and examine associations of BAG-1 expression with various clinicopathological factors and patient survival. Tumour samples were collected from 86 patients diagnosed with colorectal cancer. There was significant variation in the immunohistochemical staining patterns for BAG-1, including absent… CONTINUE READING

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