Nuclear Antigen and ASF 1 Modulate Silent Chromatin in Saccharomyces cerevisiae via Lysine 56 on Histone H 3

Abstract

The formation and stability of epigenetically regulated chromatin is influenced by DNA replication and factors that modulate post-translational modifications on histones. Here we describe evidence that PCNA can affect silencing in Saccharomyces cerevisiae by facilitating deposition of H3 K56ac onto chromosomes. We propose that PCNA participates in this… (More)

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