Nubbin encodes a POU-domain protein required for proximal-distal patterning in the Drosophila wing.

@article{Ng1995NubbinEA,
  title={Nubbin encodes a POU-domain protein required for proximal-distal patterning in the Drosophila wing.},
  author={Medard Ng and Fernando J D{\'i}az-Benjumea and Stephen Michael Cohen},
  journal={Development},
  year={1995},
  volume={121 2},
  pages={
          589-99
        }
}
The nubbin gene is required for normal growth and patterning of the wing in Drosophila. We report here that nubbin encodes a member of the POU family of transcription factors. Regulatory mutants which selectively remove nubbin expression from wing imaginal discs lead to loss of wing structures. Although nubbin is expressed throughout the wing primordium, analysis of genetic mosaics suggests a localized requirement for nubbin activity in the wing hinge. These observations suggest the existence… CONTINUE READING

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