Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells.

@article{Xiao2012Nrf3Pla2g7IP,
  title={Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells.},
  author={Qingzhong Xiao and Anna Elena Pepe and Gang Wang and Zhenling Luo and Li Zhang and Lingfang Zeng and Zhongyi Zhang and Yanhua Hu and Shu Ye and Qingbo Xu},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2012},
  volume={32 3},
  pages={730-44}
}
OBJECTIVE Phospholipase A2, group 7 (Pla2g7) is an important mediator in cardiovascular development and diseases because of its divergent physiological and pathological functions in inflammation and oxidative stress. However, little is known about the functional role of Pla2g7 in smooth muscle cell (SMC) differentiation from stem cells. METHODS AND RESULTS In the present study, embryonic stem cells were cultivated on collagen IV-coated plates to allow SMC differentiation. Pla2g7 gene… CONTINUE READING
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