Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).

@article{TimmeLaragy2012Nrf2bNZ,
  title={Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).},
  author={Alicia R Timme-Laragy and Sibel I. Karchner and Diana G. Franks and Matthew J. Jenny and Rachel C. Harbeitner and Jared Verrill Goldstone and Andrew G. McArthur and Mark E Hahn},
  journal={The Journal of biological chemistry},
  year={2012},
  volume={287 7},
  pages={
          4609-27
        }
}
NF-E2-related factor 2 (NRF2; also called NFE2L2) and related NRF family members regulate antioxidant defenses by activating gene expression via antioxidant response elements (AREs), but their roles in embryonic development are not well understood. We report here that zebrafish (Danio rerio), an important developmental model species, possesses six nrf genes, including duplicated nrf1 and nrf2 genes. We cloned a novel zebrafish nrf2 paralog, nrf2b. The predicted Nrf2b protein sequence shares… CONTINUE READING
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Molecular evolution of Keap1. Two Keap1 mole Nrf2b, Novel NRF2 Paralog in Zebrafish

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