Nrf2 signaling pathway: Pivotal roles in inflammation.

@article{Ahmed2017Nrf2SP,
  title={Nrf2 signaling pathway: Pivotal roles in inflammation.},
  author={Syed Minhaj Uddin Ahmed and Lin Luo and Akhileshwar Namani and Xiu Jun Wang and Xiuwen Tang},
  journal={Biochimica et biophysica acta. Molecular basis of disease},
  year={2017},
  volume={1863 2},
  pages={
          585-597
        }
}
  • Syed Minhaj Uddin Ahmed, Lin Luo, +2 authors Xiuwen Tang
  • Published in
    Biochimica et biophysica acta…
    2017
  • Medicine, Biology
  • Inflammation is the most common feature of many chronic diseases and complications, while playing critical roles in carcinogenesis. Several studies have demonstrated that Nrf2 contributes to the anti-inflammatory process by orchestrating the recruitment of inflammatory cells and regulating gene expression through the antioxidant response element (ARE). The Keap1 (Kelch-like ECH-associated protein)/Nrf2 (NF-E2 p45-related factor 2)/ARE signaling pathway mainly regulates anti-inflammatory gene… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 142 CITATIONS, ESTIMATED 61% COVERAGE

    Oligonol prevented the relapse of dextran sulfate sodium-ulcerative colitis through enhancing NRF2-mediated antioxidative defense mechanism.

    • K-J Kim, J-M Park, +7 authors Ki-Baik Hahm
    • Biology, Medicine
    • Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
    • 2018
    VIEW 7 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Cadmium Induces Acute Liver Injury by Inhibiting Nrf2 and the Role of NF-κB, NLRP3, and MAPKs Signaling Pathway

    VIEW 5 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2017
    2020

    CITATION STATISTICS

    • 12 Highly Influenced Citations

    • Averaged 41 Citations per year from 2017 through 2019

    • 57% Increase in citations per year in 2019 over 2018