Nrf2 signaling and redox homeostasis in the aging heart: A potential target to prevent cardiovascular diseases?

@article{SilvaPalacios2016Nrf2SA,
  title={Nrf2 signaling and redox homeostasis in the aging heart: A potential target to prevent cardiovascular diseases?},
  author={Alejandro Silva-Palacios and Mina K{\"o}nigsberg and Cecilia Zazueta},
  journal={Ageing Research Reviews},
  year={2016},
  volume={26},
  pages={81-95}
}
Aging process is often accompanied with a high incidence of cardiovascular diseases (CVD) due to the synergistic effects of age-related changes in heart morphology/function and prolonged exposure to injurious effects of CVD risk factors. Oxidative stress, considered a hallmark of aging, is also an important feature in pathologies that predispose to CVD development, like hypertension, diabetes and obesity. Approaches directed to prevent the occurrence of CVD during aging have been explored both… CONTINUE READING

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