Nrf2 sensitizes prostate cancer cells to radiation via decreasing basal ROS levels.

Abstract

Androgen deprivation therapy (ADT) was reported to lower basal ROS level in prostate cancer (PCa) and to sensitize PCa to radiation. We aimed to seek for the underlying molecular mechanism and to develop novel additive treatments to ADT in this regard. We simulated human androgen milieu in vitro and tested the ROS level in PCa cells undergoing ADT. We also… (More)
DOI: 10.1002/biof.1200

Topics

Cite this paper

@article{Liu2015Nrf2SP, title={Nrf2 sensitizes prostate cancer cells to radiation via decreasing basal ROS levels.}, author={M. X. Liu and Xu-Dong Yao and Wei Li and Jiang Geng and Yang Yan and Jian-ping Che and Yun-fei Xu and Jun-hua Zheng}, journal={BioFactors}, year={2015}, volume={41 1}, pages={52-7} }