Nrf2 and the promotion of atherosclerosis:lessons to be learned

@article{Araujo2012Nrf2AT,
  title={Nrf2 and the promotion of atherosclerosis:lessons to be learned},
  author={Jesus A. Araujo},
  journal={Clinical Lipidology},
  year={2012},
  volume={7},
  pages={123 - 126}
}
  • Jesus A. Araujo
  • Published 2012
  • Medicine
  • Clinical Lipidology
  • Abstract ,...it seems clear that Nrf2 expression can promote atherosclerosis via systemic and/or vascular local effects... despite its antioxidant actions. Therefore, should the strategy to boost endogenous antioxidant protection via Nrf2 expression be abandoned?- 
    8 Citations

    Topics from this paper

    Heme Oxygenase-1, Oxidation, Inflammation, and Atherosclerosis
    • 207
    • PDF
    Prooxidative Effects of Ambient Pollutant Chemicals Are Inhibited by HDL
    • 20
    Diesel exhaust particles and endothelial cells dysfunction: An update.
    • 26
    Inflammation, Aging, and Oxidative Stress
    • 10
    • Highly Influenced

    References

    SHOWING 1-10 OF 25 REFERENCES
    Nrf2-Keap1 defines a physiologically important stress response mechanism.
    • 1,299
    Nrf2 is essential for protection against acute pulmonary injury in mice.
    • K. Chan, Y. Kan
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1999
    • 555
    • PDF
    Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism.
    • 137
    • PDF
    Antioxidant therapy and atherosclerosis: animal and human studies.
    • 55
    Role of oxidative modifications in atherosclerosis.
    • 2,337
    • PDF