Nrf2 and Redox Status in Prediabetic and Diabetic Patients

@inproceedings{JimnezOsorio2014Nrf2AR,
  title={Nrf2 and Redox Status in Prediabetic and Diabetic Patients},
  author={Ang{\'e}lica Sara{\'i} Jim{\'e}nez-Osorio and Alejandra Picazo and Susana Gonz{\'a}lez-Reyes and Diana Barrera-Oviedo and Martha Eunice Rodr{\'i}guez-Arellano and Jos{\'e} Pedraza-Chaverr{\'i}},
  booktitle={International journal of molecular sciences},
  year={2014}
}
The redox status associated with nuclear factor erythroid 2-related factor-2 (Nrf2) was evaluated in prediabetic and diabetic subjects. Total antioxidant status (TAS) in plasma and erythrocytes, glutathione (GSH) and malondialdehyde (MDA) content and activity of antioxidant enzymes were measured as redox status markers in 259 controls, 111 prediabetics and 186 diabetic type 2 subjects. Nrf2 was measured in nuclear extract fractions from peripheral blood mononuclear cells (PBMC). Nrf2 levels… CONTINUE READING
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Activation of the Nrf2-ARE pathway attenuates hyperglycemia-mediated injuries in mouse podocytes.

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