Nrf2 and Cardiovascular Defense

@inproceedings{Howden2013Nrf2A,
  title={
Nrf2 and Cardiovascular Defense},
  author={Reuben Howden},
  booktitle={Oxidative medicine and cellular longevity},
  year={2013}
}
The cardiovascular system is susceptible to a group of diseases that are responsible for a larger proportion of morbidity and mortality than any other disease. Many cardiovascular diseases are associated with a failure of defenses against oxidative stress-induced cellular damage and/or death, leading to organ dysfunction. The pleiotropic transcription factor, nuclear factor-erythroid (NF-E) 2-related factor 2 (Nrf2), regulates the expression of antioxidant enzymes and proteins through the… CONTINUE READING
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