Nrf2: control of sensitivity to carcinogens

@article{Slocum2011Nrf2CO,
  title={Nrf2: control of sensitivity to carcinogens},
  author={Stephen L. Slocum and Thomas Wells Kensler},
  journal={Archives of Toxicology},
  year={2011},
  volume={85},
  pages={273-284}
}
Induction of enzymes that enhance the detoxication of chemical carcinogens has been a broadly effective strategy for chemoprevention of experimental carcinogenesis in rodent models. Several inducing agents are now in clinical trials to evaluate utility for prevention of cancers associated with unavoidable high exposures to environmental carcinogens. The successes of these pre-clinical and clinical interventions lead to studies to define the molecular basis for protection by these agents, which… CONTINUE READING
Highly Cited
This paper has 156 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 90 citations

157 Citations

0102030'12'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 157 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 84 references