Nramp1 phagocyte intracellular metal withdrawal defense.

  title={Nramp1 phagocyte intracellular metal withdrawal defense.},
  author={Mathieu F. M. Cellier and Pascal Courville and Carole G. Campion},
  journal={Microbes and infection},
  volume={9 14-15},
Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases. 

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