Nramp1 phagocyte intracellular metal withdrawal defense.

@article{Cellier2007Nramp1PI,
  title={Nramp1 phagocyte intracellular metal withdrawal defense.},
  author={Mathieu F. M. Cellier and Pascal Courville and Carole G. Campion},
  journal={Microbes and infection},
  year={2007},
  volume={9 14-15},
  pages={1662-70}
}
Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases. 

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

Similar Papers

Loading similar papers…