Npas1+ Pallidal Neurons Target Striatal Projection Neurons

@article{Glajch2016Npas1PN,
  title={Npas1+ Pallidal Neurons Target Striatal Projection Neurons},
  author={Kelly E. Glajch and Daniel A. Kelver and Daniel J. Hegeman and Qiaoling Cui and H. Xenias and Elizabeth C. Augustine and V. Hern{\'a}ndez and N. Verma and T. Huang and M. Luo and N. Justice and C. S. Chan},
  journal={The Journal of Neuroscience},
  year={2016},
  volume={36},
  pages={5472 - 5488}
}
Compelling evidence demonstrates that the external globus pallidus (GPe) plays a key role in processing sensorimotor information. An anatomical projection from the GPe to the dorsal striatum has been described for decades. However, the cellular target and functional impact of this projection remain unknown. Using cell-specific transgenic mice, modern monosynaptic tracing techniques, and optogenetics-based mapping, we discovered that GPe neurons provide inhibitory inputs to direct and indirect… Expand
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