Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin

@article{Bandell2004NoxiousCI,
  title={Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin},
  author={Michael Bandell and Gina M. Story and Sun Wook Hwang and Veena Viswanath and Samer R. Eid and Matt J. Petrus and Taryn J. Earley and Ardem Patapoutian},
  journal={Neuron},
  year={2004},
  volume={41},
  pages={849-857}
}

Figures from this paper

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
The nervous system senses peripheral damage through nociceptive neurons that transmit a pain signal. TRPA1 is a member of the Transient Receptor Potential (TRP) family of ion channels and is
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