Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice

@inproceedings{Moe2011Nox2AN,
  title={Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice},
  author={Kyaw Thu Moe and Nwe Oo Yin and Tin Maung Naylynn and Katwadi Khairunnisa and M A Wutyi and Yusu Gu and Mohamed Shirhan Bin Mohamed Atan and Meng Cheong Wong and Tian Hai Koh and Philip Wong},
  booktitle={Journal of cellular and molecular medicine},
  year={2011}
}
Reactive oxygen species (ROS) and pro-inflammatory cytokines are crucial in ventricular remodelling, such as inflammation-associated myocarditis. We previously reported that tumour necrosis factor-α (TNF-α)-induced ROS in human aortic smooth muscle cells is mediated by NADPH oxidase subunit Nox4. In this study, we investigated whether TNF-α-induced ventricular remodelling was mediated by Nox2 and/or Nox4. An intravenous injection of murine TNF-α was administered to a group of mice and saline… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

QSYQ Attenuates Oxidative Stress and Apoptosis Induced Heart Remodeling Rats through Different Subtypes of NADPH-Oxidase

Evidence-based complementary and alternative medicine : eCAM • 2013
View 9 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology • 2009
View 2 Excerpts

Localization of mesenchymal cells in adult mouse thymus: their abnormal distribution in mice with disorganization of thymic medullary epithelium.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society • 2009
View 1 Excerpt

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro.

American journal of physiology. Heart and circulatory physiology • 2009
View 1 Excerpt

Doppler myocardial imaging in adult male rats: reference values and reproducibility of velocity and deformation parameters.

European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology • 2006
View 1 Excerpt

Similar Papers

Loading similar papers…