Nowadays which emergency contraception? Comparison between past and present: latest news in terms of clinical efficacy, side effects and contraindications

@article{Gizzo2012NowadaysWE,
  title={Nowadays which emergency contraception? Comparison between past and present: latest news in terms of clinical efficacy, side effects and contraindications},
  author={S. Gizzo and T. Fanelli and S. di Gangi and C. Saccardi and T. S. Patrelli and A. Zambon and Anis Omar and D. D'Antona and G. Nardelli},
  journal={Gynecological Endocrinology},
  year={2012},
  volume={28},
  pages={758 - 763}
}
Despite many highly effective methods of contraception are available nowadays, many pregnancies are unintended. Emergency contraception (EC) is the use of drug or device after unprotected intercourse to prevent an unwanted pregnancy. It is a woman’s last chance to prevent unintended pregnancy. Nevertheless the confusion about mechanisms of action, side effects, clinical efficacy and controindications makes the intervention underused in every setting investigated. So far levonorgestrel (LNG) has… Expand
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References

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TLDR
Evidence is provided that UPA, a new type of second-generation progesterone receptor modulator, represents a new evolutionary step in EC treatment and is in line with results from a series of clinical trials conducted recently which demonstrate that U PA seems to have higher EC efficacy compared to LNG. Expand
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An overview of the history of EC methods and the current availability of oral and intrauterine EC methods is provided and Clinicians should be aware of all available options in order to counsel women in need of EC appropriately. Expand
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Mifepristone middle dose (25-50 mg) was superior to other hormonal regimens and Levonorgestrel was more effective than the Yuzpe regimen in preventing pregnancy. Expand
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TLDR
The female menstrual cycle comprises three distinct phases: follicular, ovulatory, and luteal; ulipristal acetate was developed to be a derivative of 19-norprogesterone, and the drug is used to prevent unintended pregnancy for up to five days after unprotected intercourse or contraceptive failure. Expand
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Ulipristal acetate is effective and well-tolerated for emergency contraception 48–120 hours after unprotected intercourse, and this results satisfy the protocol-defined statistical criteria for success. Expand
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