Novelty seeking and drug use: contribution of an animal model.

  title={Novelty seeking and drug use: contribution of an animal model.},
  author={Mary Eileen Cain and Donald A. Saucier and Michael T. Bardo},
  journal={Experimental and clinical psychopharmacology},
  volume={13 4},
Although sensation seeking or novelty seeking is a reliable predictor of drug use in humans, individual differences in free-choice novelty seeking in animal models have generally failed to predict drug use. In the current article, hierarchical multiple regression analyses were used on data collected from a large sample of rats. Rats were screened on measures of inescapable and free-choice novelty tests and then were trained to lever press for sucrose or intravenous amphetamine. Although scores… CONTINUE READING

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