Novel water-soluble phthalocyanines substituted with phosphonate moieties on the benzo rings

@inproceedings{Sharman1996NovelWP,
  title={Novel water-soluble phthalocyanines substituted with phosphonate moieties on the benzo rings},
  author={Wesley M. Sharman and Svetlana V. Kudrevich and Johan E. van Lier},
  year={1996}
}
Abstract The synthesis and characterization of a series of phthalocyanine derivatives bearing phosphonate substituents directly bound to the aromatic rings of the phthalocyanine is described. These novel water-soluble phthalocyanine tetraphosphonates are of interest for different applications, particularly as photosensitizers in photodynamic therapy. Furthermore, this synthetic approach allows for more versatility in the preparation of hydrophilic macrocycles. 

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Synthesis and characterization of novel zinc phthalocyanines as potential photosensitizers for photodynamic therapy of cancers.

  • Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
  • 2014

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Selected spectroscopic data: HRMS (EI) Theor

2 Compound
  • 264.0664 Exp. 264.0660. IR v/cm -1 (KBr) 3096, 3066, 3035 (atom C-H), 2974, 2934, 2895 (aliph. C-H), 2235 (C-N), 1232 (phosphate ester P=O), and 1093-1049 (P-O-C). 300 MHz 1H NMR 8 (DMSO-d6) 8.0-8.2 (3H, m, aromatic), 3.3 5834 (4H, b, CH 2 ester) and 0.9-1.0 (6H, t, CH3). 300 MHz 13C NMR 8 (DMSO-d6