Novel use of ultrasound to examine regional blood flow in the mouse kidney.

@article{Sullivan2009NovelUO,
  title={Novel use of ultrasound to examine regional blood flow in the mouse kidney.},
  author={J. Charlie Sullivan and Bin Wang and Erika I. Boesen and Gerard D'Angelo and Jennifer S. Pollock and David M. Pollock},
  journal={American journal of physiology. Renal physiology},
  year={2009},
  volume={297 1},
  pages={F228-35}
}
Conventional methods used for measuring regional renal blood flow, such as laser-Doppler flowmetry, are highly invasive, and each measurement is restricted to a discrete location. The aim of this study was to determine whether ultrasound imaging in conjunction with enhanced contrast agent (microbubbles; Vevo MicroMarker, VisualSonics) could provide a viable noninvasive alternative. This was achieved by determining changes in renal cortical and medullary rate of perfusion in response to a bolus… CONTINUE READING