Novel trichomonacidal spermicides.

@article{Jain2011NovelTS,
  title={Novel trichomonacidal spermicides.},
  author={Ashish Jain and Nand Lal and Vijay Kumar and Vikas Verma and R. Magesh Kumar and Lalit Kumar and Vishal Singh and Raghav Kumar Mishra and Amit Sarswat and Sanjay K Jain and Jagdamba Prasad Maikhuri and Vishnu Dutt Sharma and Gopal N. Gupta},
  journal={Antimicrobial agents and chemotherapy},
  year={2011},
  volume={55 9},
  pages={
          4343-51
        }
}
Metronidazole, the U.S. Food and Drug Administration-approved drug against trichomoniasis, is nonspermicidal and thus cannot offer pregnancy protection when used vaginally. Furthermore, increasing resistance of Trichomonas vaginalis to 5-nitro-imidazoles is a cause for serious concern. On the other hand, the vaginal spermicide nonoxynol-9 (N-9) does not protect against sexually transmitted diseases and HIV in clinical situations but may in fact increase their incidence due to its nonspecific… CONTINUE READING

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