Novel trabecular meshwork inducible glucocorticoid response mutation in an eight-generation juvenile-onset primary open-angle glaucoma pedigree.

Abstract

OBJECTIVE This study aimed to update a large kindred with juvenile-onset primary open-angle glaucoma (POAG) first described in 1940 and to identify the underlying genetic cause of the disease. DESIGN Molecular genetic study of a single kindred, including clinical examination, retrospective review of clinical and family history records, linkage analysis… (More)

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@article{Richards1998NovelTM, title={Novel trabecular meshwork inducible glucocorticoid response mutation in an eight-generation juvenile-onset primary open-angle glaucoma pedigree.}, author={Julia E. Richards and Robert Ritch and Paul R. Lichter and Frank W. Rozsa and Heather M Stringham and Ronald M Caronia and Dannette S. Johnson and G P Abundo and James R. Willcockson and Catherine A. Downs and Debra A. Thompson and Maria A. Musarella and Narmada Prasad Gupta and Mohammad I. Othman and Daniel M Torrez and Sean B. Herman and Deborah J.L. Wong and Mikito Higashi and Michael Boehnke}, journal={Ophthalmology}, year={1998}, volume={105 9}, pages={1698-707} }