Novel toxins from type II toxin-antitoxin systems with acetyltransferase activity.

@article{Jurnas2017NovelTF,
  title={Novel toxins from type II toxin-antitoxin systems with acetyltransferase activity.},
  author={Dukas Jurėnas and Abel Garcia-Pino and Laurence Van Melderen},
  journal={Plasmid},
  year={2017},
  volume={93},
  pages={30-35}
}
Type II toxin-antitoxin (TA) systems are widespread in bacterial and archeal genomes. These modules are very dynamic and participate in bacterial genome evolution through horizontal gene transfer. TA systems are commonly composed of a labile antitoxin and a stable toxin. Toxins appear to preferentially inhibit the protein synthesis process. Toxins use a variety of molecular mechanisms and target nearly every step of translation to achieve their inhibitory function. This review focuses on a… CONTINUE READING
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