Novel topological features of FhaC, the outer membrane transporter involved in the secretion of the Bordetella pertussis filamentous hemagglutinin.

@article{Gudin2000NovelTF,
  title={Novel topological features of FhaC, the outer membrane transporter involved in the secretion of the Bordetella pertussis filamentous hemagglutinin.},
  author={S Gu{\'e}din and Eve Willery and Jan P Tommassen and Esther Fort and Herv{\'e} Drobecq and Camille Locht and Françoise Jacob-Dubuisson},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 39},
  pages={30202-10}
}
Many pathogenic Gram-negative bacteria secrete virulence factors across the cell envelope into the extracellular milieu. The secretion of filamentous hemagglutinin (FHA) by Bordetella pertussis depends on the pore-forming outer membrane protein FhaC, which belongs to a growing family of protein transporters. Protein alignment and secondary structure… CONTINUE READING