Novel therapies for children with acute myeloid leukaemia

@article{Moore2013NovelTF,
  title={Novel therapies for children with acute myeloid leukaemia},
  author={Andrew S Moore and Pamela R. Kearns and Steven Knapper and Andrew D. J. Pearson and Ch Michel Zwaan},
  journal={Leukemia},
  year={2013},
  volume={27},
  pages={1451-1460}
}
Significant improvements in survival for children with acute myeloid leukaemia (AML) have been made over the past three decades, with overall survival rates now approximately 60–70%. However, these gains can be largely attributed to more intensive use of conventional cytotoxics made possible by advances in supportive care, and although over 90% of children achieve remission with frontline therapy, approximately one third in current protocols relapse. Furthermore, late effects of therapy cause… CONTINUE READING
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