Novel therapeutic usage of low-dose doxepin hydrochloride

@article{Singh2007NovelTU,
  title={Novel therapeutic usage of low-dose doxepin hydrochloride},
  author={Haramandeep Singh and Philip M. Becker},
  journal={Expert Opinion on Investigational Drugs},
  year={2007},
  volume={16},
  pages={1295 - 1305}
}
  • H. Singh, P. Becker
  • Published 1 August 2007
  • Medicine, Psychology
  • Expert Opinion on Investigational Drugs
Low-dose doxepin hydrochloride (1, 3 and 6 mg) is a tricyclic antidepressant currently being investigated for the treatment of primary insomnia in adult and geriatric patients. Although it has been used at much higher doses to treat depression effectively for a number of decades, it offers a unique potency and selectivity for antagonizing the H1 (histamine) receptor at low doses. This mechanism of action may prove to be advantageous compared with other medications currently approved for the… 

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