Novel testis-expressed profilin IV associated with acrosome biogenesis and spermatid elongation.

@article{Obermann2005NovelTP,
  title={Novel testis-expressed profilin IV associated with acrosome biogenesis and spermatid elongation.},
  author={Heike Obermann and Inka Raabe and Marga Balvers and B{\"a}rbel Brunswig and Wolfgang Schulze and Christiane Kirchhoff},
  journal={Molecular human reproduction},
  year={2005},
  volume={11 1},
  pages={53-64}
}
A novel profilin, named profilin IV, was cloned and characterized as a testicular isoform, distinct from the previously described testis-specific profilin III. Profilin IV showed only 30% amino acid identity with the other mammalian profilins; nevertheless, database searches produced significant alignments with the conserved profilin domain. Northern blot analysis and in situ transcript hybridization suggested that profilin IV, like profilin III, is transcribed in the germ cells. However, the… CONTINUE READING

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Annals of the New York Academy of Sciences • 1952
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