Novel tastes elevate c-fos expression in the central amygdala and insular cortex: implication for taste aversion learning.

@article{Koh2003NovelTE,
  title={Novel tastes elevate c-fos expression in the central amygdala and insular cortex: implication for taste aversion learning.},
  author={Ming Teng Koh and Emily E Wilkins and I. Leonard Bernstein},
  journal={Behavioral neuroscience},
  year={2003},
  volume={117 6},
  pages={1416-22}
}
Taste novelty strongly modulates the speed and strength of taste aversion conditioning. To identify molecular signals responsive to novel tastes, immunostaining for c-fos protein (Fos-like immunoreactivity [FLI]) was used to mark neurons that responded differentially to taste novelty. Novel saccharin induced larger increases in FLI than familiar saccharin. This pattern was seen in central amygdala and insular cortex, but not in basolateral amygdala, parabrachial nucleus, or nucleus of the… CONTINUE READING

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