Novel targets in the treatment of advanced gastric cancer: a perspective review.

@article{Fontana2016NovelTI,
  title={Novel targets in the treatment of advanced gastric cancer: a perspective review.},
  author={Elisa Fontana and Elizabeth C. Smyth},
  journal={Therapeutic advances in medical oncology},
  year={2016},
  volume={8 2},
  pages={113-25}
}
Gastric cancer is responsible for a high burden of disease globally. Although more extensive use of chemotherapy together with the recent introduction of the two targeted agents trastuzumab and ramucirumab have contributed to marginal outcome prolongation, overall survival for patients with advanced stage disease remains poor. Over the last decade, a number of novel agents have been examined in clinical trials with largely disappointing results. Potential explanations for this are the absence… CONTINUE READING
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