Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.

@article{Xu2013NovelSV,
  title={Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.},
  author={Heng Li Xu and Wenjian Yang and Virginia P{\'e}rez-Andreu and Meenakshi Devidas and Yiping Fan and Cheng Cheng and Deqing Pei and Paul Scheet and Esteban Gonz{\`a}lez Burchard and Celeste Eng and Scott Huntsman and Dara G. Torgerson and Michael Jon Dean and Naomi Joan Winick and Paul Langlie Martin and Bruce M. Camitta and W. Paul Bowman and Cheryl Willman and William L Carroll and Charles G Mullighan and Deepa Bhojwani and Stephen P Hunger and Ching-Hon Pui and Williams E Evans and Mary V. Relling and Mignon L Loh and Jun J. Yang},
  journal={Journal of the National Cancer Institute},
  year={2013},
  volume={105 10},
  pages={
          733-42
        }
}
BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common cancer in children and the incidence of ALL varies by ethnicity. Although accumulating evidence indicates inherited predisposition to ALL, the genetic basis of ALL susceptibility in diverse ancestry has not been comprehensively examined. METHODS We performed a multiethnic genome-wide association study in 1605 children with ALL and 6661 control subjects after adjusting for population structure, with validation in three… CONTINUE READING
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