Novel strategy for inhibiting viral entry by use of a cellular receptor-plant virus chimera.

@article{Khor2002NovelSF,
  title={Novel strategy for inhibiting viral entry by use of a cellular receptor-plant virus chimera.},
  author={Ing Wei Khor and Tianwei Lin and Johannes P Langedijk and John E. Johnson and M. Addison Manchester},
  journal={Journal of virology},
  year={2002},
  volume={76 9},
  pages={4412-9}
}
The plant virus cowpea mosaic virus (CPMV) has recently been developed as a biomolecular platform to display heterologous peptide sequences. Such CPMV-peptide chimeras can be easily and inexpensively produced in large quantities from experimentally infected plants. This study utilized the CPMV chimera platform to create an antiviral against measles virus (MV) by displaying a peptide known to inhibit MV infection. This peptide sequence corresponds to a portion of the MV binding site on the human… CONTINUE READING

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The plant virus cowpea mosaic virus ( CPMV ) has recently been developed as a biomolecular platform to display heterologous peptide sequences .
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