Novel strategy for generation of mucosal immune responses against HIV-1 following systemic vaccination


A significant hurdle in effective vaccine design for infectious pathogens is the ability to mount immune responses at the portal of entry, namely mucosal sites. The development of a systemic-delivered vaccine approach driving secretory IgA and mucosal T cell immune responses against pathogens would fundamentally change many vaccine strategies. Using mucosal… (More)
DOI: 10.1186/1742-4690-3-S1-S30