Novel simian immunodeficiency virus CTL epitopes restricted by MHC class I molecule Mamu-B*01 are highly conserved for long term in DNA/MVA-vaccinated, SHIV-challenged rhesus macaques.

@article{Su2005NovelSI,
  title={Novel simian immunodeficiency virus CTL epitopes restricted by MHC class I molecule Mamu-B*01 are highly conserved for long term in DNA/MVA-vaccinated, SHIV-challenged rhesus macaques.},
  author={Jin Lian Su and Mark A. Luscher and Yelin Xiong and Tarick Rustam and Rama Rao Amara and Eva G Rakasz and Harriet L Robinson and Kelly S Macdonald},
  journal={International immunology},
  year={2005},
  volume={17 5},
  pages={637-48}
}
Simian immunodeficiency virus (SIV) infection of rhesus macaques provides an excellent model for investigating the basis of protective immunity against human immunodeficiency virus (HIV). One limitation of this model, however, has been the availability of a small number of known MHC class I-restricted CTL epitopes for investigating virus-specific immune responses. We assessed CTL responses against SIV Gag in a cohort of DNA/modified vaccinia virus Ankara (MVA)-vaccinated/simian-human… CONTINUE READING

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