Novel significant stage-specific differentially expressed genes in hepatocellular carcinoma

@article{Sarathi2019NovelSS,
  title={Novel significant stage-specific differentially expressed genes in hepatocellular carcinoma},
  author={Arjun Sarathi and A. Palaniappan},
  journal={BMC Cancer},
  year={2019},
  volume={19}
}
BackgroundLiver cancer is among top deadly cancers worldwide with a very poor prognosis, and the liver is a vulnerable site for metastases of other cancers. Early diagnosis is crucial for treatment of the predominant liver cancers, namely hepatocellular carcinoma (HCC). Here we developed a novel computational framework for the stage-specific analysis of HCC.MethodsUsing publicly available clinical and RNA-Seq data of cancer samples and controls and the AJCC staging system, we performed a linear… Expand
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