Novel sesterterpenes from Leucosceptrum canum of nepalese origin.

  title={Novel sesterterpenes from Leucosceptrum canum of nepalese origin.},
  author={M. Choudhary and R. Ranjit and Atta-ur-Rahman and Sajjad Hussain and K. P. Devkota and T. M. Shrestha and M. Parvez},
  journal={Organic letters},
  volume={6 23},
Two novel sesterterpenoids, leucosesterterpenone (1) and leucosesterlactone (2), with novel skeleta were isolated from the hexane extract of the medicinal plant, Leucosceptrum canum. Their structures were established by the analysis of NMR data and the single-crystal X-ray diffraction of compound 1. Compounds 1 and 2 were found to exhibit activity against prolylendopeptidase (PEP). 
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