Novel sesquiterpene and coumarin constituents from the whole herbs of Crossostephium chinense

  title={Novel sesquiterpene and coumarin constituents from the whole herbs of Crossostephium chinense},
  author={Qi Wu and Lei Zou and Xiu Wei Yang and Dexian Fu},
  journal={Journal of Asian Natural Products Research},
  pages={85 - 90}
  • Qi WuLei Zou Dexian Fu
  • Published 1 January 2009
  • Chemistry
  • Journal of Asian Natural Products Research
Novel sesquiterpene, named crossostephin (1), and coumarin, named biscopoletin (2), together with four known compounds, artesin, tanacetin, scopoletin, and scopolin, were isolated from the 70% ethanolic extract of the whole herbs of Crossostephium chinense (L.) Makino. Their structures were determined by spectroscopic methods, including IR, UV, EIMS, HRFTICRMS, 1D and 2D NMR spectral analyses. Both scopoletin and scopolin were isolated from the title plant for the first time. 

Further Characterization of Foliar Flavonoids in Crossostephium chinense and their Geographic Variation

It was shown by HPLC survey that variation of the species’ flavonoids occurs among the collection sites.

2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins

2-Oxoglutarate-dependent dioxygenases from plants convert cinnamate derivatives into simple coumarins through the process of ortho-hydroxylation, which describes the 2OGDs involved in coumarin biosynthesis and their substrate specificities.

The complete chloroplast genome of Crossostephium chinense (Asteraceae), using genome skimming data

Phylogenetic analysis indicates that C. chinense is sister to Artemisia annua and Artemisia fukudo, and not only assembled its complete chloroplast genome, but also reconstructed the phylogenetic relationship between C. Chinense and ArtemisIA.

Sesquiterpenoids from Seriphidium transiliense and Their Melanogenic Activity.

A sesquiterpenoid with an unprecedented 5/5/4 tricyclic skeleton (1), a nor-sesquiterpenoid with a rare 6/7 bicyclic skeleton (2), 10 new sesquiterpenoids (3-12), and six known analogues (13-18) were

Development of Genomic Resources From Crossostephium Chinense (Asteraceae) Based on Genome Skimming Data

This study performed for the first-ever study on employment of genome skimming data and CandiSSR, consequently a total of 133 polymorphic nSSRs were developed and cross-amplifications were successful done for C. chinense and Artemisia.

Hepatoprotective effect of Crossostephium chinensis (L.) Makino in rats.

CCW inhibited the expression of M MP-9 protein, indicating that MMP-9 played an important role in the development of CCl(4)-induced chronic liver damage in rats.

Chemical Constituents of the Fruit Husk of Xanthoceras sorbifolia

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Coumarin and Secoiridoid Glucosides from Bark of Olea africana and Olea capensis

Coumarin glucosides, esculin (1) and scopolin (2), were isolated from the bark of Olea africana MILL. (O. europaea L. subsp. africana (MILL.) GREEN) while isoscopoletin-β-D-glucoside (magnolioside)

New cytotoxic sesquiterpene lactones from Warionia saharae.

Cytotoxicity-guided fractionation of the methanol soluble part of the dichloromethane extract of the leaves of Warionia saharae led to the isolation of the two new guaianolide-type sesquiterpene lactones, which were isolated together with the known flavone hispidulin.

DMSO-d 6 ) and 13 C NMR (75 MHz, DMSO-d 6 ) spectral data, in Table 2, which were in good agreement with those reported for scopoletin

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    Scopolin (4) Colorless needles (MeOH)


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      893, 680; 1 H NMR (500 MHz, CDCl 3 ) and 13 C NMR (125 MHz, CDCl 3 ) spectral data were shown in Table 1