Novel serum and urine markers for pediatric appendicitis.

  title={Novel serum and urine markers for pediatric appendicitis.},
  author={Anupam B Kharbanda and Alex J. Rai and Yohaimi Cosme and Khin M Liu and Peter S. Dayan},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  volume={19 1},
OBJECTIVES The objective was to describe the association between two novel biomarkers, calprotectin and leucine-rich alpha glycoprotein-1 (LRG), and appendicitis in children. METHODS This was a prospective, cross-sectional study of children 3 to 18 years old presenting to a pediatric emergency department (ED) with possible appendicitis. Blood and urine samples were assayed for calprotectin and LRG via enzyme-linked immunosorbent assay (ELISA). Final diagnosis was determined by histopathology… CONTINUE READING
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