Novel screening methods--biosensors.

  title={Novel screening methods--biosensors.},
  author={Lothar Eggeling and Michael Bott and Jan Marienhagen},
  journal={Current opinion in biotechnology},
Biosensors offer exciting possibilities for improving cells or enzymes as biocatalysts for the synthesis of small molecules. We here review recent progress in the development and the screening applications of transcription-factor-based biosensors. An example is a cofactor-dependent biosensor which provides a generalizable screen for NADPH-dependent enzymes. Another example is the use of a biosensor in combination with recombineering for strain development, thereby expanding the genome… CONTINUE READING

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subtilis E . coli GFP FACS Demonstration of kaempferol responsiveness due to added dehydrokampferol and different activities of a flavonol synthase from Arabidopsis thaliana

  • B. QdoR
  • Current Opinion in Biotechnology
  • 2015

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