Novel roles of Vmp1: inhibition metastasis and proliferation of hepatocellular carcinoma.

@article{Guo2012NovelRO,
  title={Novel roles of Vmp1: inhibition metastasis and proliferation of hepatocellular carcinoma.},
  author={Lei Guo and Lian-yue Yang and Chun Fan and Guo-dong Chen and Fan Wu},
  journal={Cancer science},
  year={2012},
  volume={103 12},
  pages={2110-9}
}
Hepatocellular carcinoma (HCC) is one of the most deadly human cancers because of its high incidence of metastasis. Despite extensive efforts, therapies against metastasis of HCC remain underdeveloped. Vacuole membrane protein 1 (Vmp1) was recently identified to be involved in cancer-relevant processes; however, its expression, clinical significance and biological function in HCC progression are still unknown. Therefore, we evaluated the expression of Vmp1 in human HCC specimens. To… CONTINUE READING

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