Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells.

@article{Ma2015NovelRO,
  title={Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells.},
  author={Wenbo Ma and Caiyue Li and Shikui Yin and Jingxin Liu and Chao Gao and Zuoxian Lin and Rongqi Huang and Ju-Fang Huang and Zhi-yuan Li},
  journal={Free radical biology & medicine},
  year={2015},
  volume={89},
  pages={1003-13}
}
Oxidative stress is important for the initiation and progression of cancers, which confers the cells with a survival advantage by inducing oxidative adaption and drug resistance. Therefore, developing strategies to promote oxidative stress-induced cytotoxicity could be important for cancer therapy. Herein, we found that H2O2-mediated oxidative stress… CONTINUE READING