Novel role of 1,25(OH)(2)D(3) in induction of erythroid progenitor cell proliferation.

@article{Alon2002NovelRO,
  title={Novel role of 1,25(OH)(2)D(3) in induction of erythroid progenitor cell proliferation.},
  author={Dora Ben Alon and Cidio Chaimovitz and Alexander Dvilansky and Gilles Lugassy and Amos Douvdevani and Shraga Shany and Ilana Nathan},
  journal={Experimental hematology},
  year={2002},
  volume={30 5},
  pages={403-9}
}
OBJECTIVE Burst-forming unit erythroid and colony-forming unit erythroid growth in vitro is lower in studies of continuous ambulatory peritoneal dialysis patients than healthy controls. Burst-forming unit erythroid growth was potentiated by addition of 1alpha,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and normalized by erythropoietin (Epo) therapy, suggesting an interaction between Epo and 1,25(OH)(2)D(3) at the stem cell level. The objective of this study was to determine the mechanism by… CONTINUE READING
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