Novel role for the pontine micturition center, Barrington's nucleus: evidence for coordination of colonic and forebrain activity.

@article{Pavcovich1998NovelRF,
  title={Novel role for the pontine micturition center, Barrington's nucleus: evidence for coordination of colonic and forebrain activity.},
  author={L A Pavcovich and Mu Yang and Richard R Miselis and Rita J Valentino},
  journal={Brain research},
  year={1998},
  volume={784 1-2},
  pages={355-61}
}
This report provides evidence for a novel role of Barrington's nucleus, considered the pontine micturition center, in regulation of colonic function. Barrington's activation elicited increases in colonic intraluminal pressure that were eliminated by scopolamine and intrathecal lidocaine, suggesting an impact of Barrington's neurons on colonic activity via projections to lumbosacral parasympathetic neurons. Consistent with this, Barrington's neurons were transsynaptically labeled from the distal… CONTINUE READING
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