Novel regions of amplification on 8q distinct from the MYC locus and frequently altered in oral dysplasia and cancer.

@article{Garnis2004NovelRO,
  title={Novel regions of amplification on 8q distinct from the MYC locus and frequently altered in oral dysplasia and cancer.},
  author={Cathie Garnis and Bradley P. Coe and Adrian S Ishkanian and Lewei Zhang and Miriam Pearl Rosin and Wan L. Lam},
  journal={Genes, chromosomes & cancer},
  year={2004},
  volume={39 1},
  pages={93-8}
}
Genetic studies aimed at identifying key alterations in oral cancers have focused on analysis of tumors, with few such studies using early oral premalignant lesions (OPLs) because of limitations in both sample availability and size. In this study, we used a randomly amplified polymorphic DNA (RAPD)-PCR approach to fingerprint DNA from microdissected normal and dysplastic cells and identified two recurrent genetic alterations on the long arm of chromosome 8 in OPLs, one mapping to 8q22 and the… CONTINUE READING
25 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Similar Papers

Loading similar papers…