Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells.

@article{Wang1999NovelRP,
  title={Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells.},
  author={J. Wang and Toshiyuki Takeuchi and Haruo Yokota and Tetsuro Izumi},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 40},
  pages={28542-8}
}
A novel rabphilin-3-like gene, granuphilin, has been identified in pancreatic beta cells by comparing genes expressed in pancreatic alpha and beta cell lines using mRNA differential display. The domain structure of the protein products of the granuphilin gene contains an amino-terminal zinc-finger motif and carboxyl-terminal C(2)-domains, similar to that of the rabphilin-3 gene. There are two isoforms: the larger isoform, granuphilin-a, has two C(2)-domains, whereas the smaller one, granuphilin… CONTINUE READING

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Protein in Pancreatic Beta Cells 28548 by gest on July 10

Chung, S.-H, Y. Takai, R. W. Holz
J. Biol. Chem. 270, • 1995
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