Novel plant SUN–KASH bridges are involved in RanGAP anchoring and nuclear shape determination

@inproceedings{Zhou2012NovelPS,
  title={Novel plant SUN–KASH bridges are involved in RanGAP anchoring and nuclear shape determination},
  author={Xiao Ying Zhou and Katja Graumann and David E. Evans and Iris Meier},
  booktitle={The Journal of cell biology},
  year={2012}
}
Inner nuclear membrane Sad1/UNC-84 (SUN) proteins interact with outer nuclear membrane (ONM) Klarsicht/ANC-1/Syne homology (KASH) proteins, forming linkers of nucleoskeleton to cytoskeleton conserved from yeast to human and involved in positioning of nuclei and chromosomes. Defects in SUN-KASH bridges are linked to muscular dystrophy, progeria, and cancer. SUN proteins were recently identified in plants, but their ONM KASH partners are unknown. Arabidopsis WPP domain-interacting proteins… CONTINUE READING
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