Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.

@article{Yoshikawa2010NovelPC,
  title={Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.},
  author={Kazuko Yoshikawa and Naoki Kokudo and Toshihiro Hashimoto and Kyosuke Yamamoto and Toshiaki Inose and Takashi Kimura},
  journal={Biological & pharmaceutical bulletin},
  year={2010},
  volume={33 8},
  pages={1355-9}
}
Sparassis crispa (SC), known as Hanabiratake in Japanese, is an edible mushroom with various medicinal properties. We isolated 3 novel phthalides, designated hanabiratakelide A (1), B (2), and C (3), from the SC fruit body. In this investigation, 3 known phthalides (4-6), ubiquinone-9, and 2 known unsaturated fatty acids were also isolated. Their structures were elucidated primarily through extensive NMR experiments. The isolated compounds 1-6 were tested for their anti-oxidant activity. The in… CONTINUE READING