Novel pharmacological approaches for antiarrhythmic therapy

@article{Ravens2009NovelPA,
  title={Novel pharmacological approaches for antiarrhythmic therapy},
  author={Ursula Ravens},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2009},
  volume={381},
  pages={187-193}
}
Arrhythmias are caused by the perturbation of physiological impulse formation, impaired conduction, or disturbed electrical recovery. Currently available antiarrhythmic drugs—perhaps with exception of amiodarone—are not sufficiently effective and are burdened by cardiac and extracardiac side effects that may offset their therapeutic benefits. Detailed knowledge about electrical and structural remodelling may provide a better understanding of the mechanisms leading to generation and maintenance… CONTINUE READING

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