Novel one-pot process for the synthesis of 1,3-thiazoles via organocatalysed epoxidation of nitro-olefins.

Abstract

A facile one-pot two-step process for the synthesis of 1,3-thiazole heterocycles via organocatalytic epoxidation of nitro-olefins with the t-BuOOH/DBU system, and subsequent reaction of α-nitro-epoxides with thioamides under mild conditions has been developed.

DOI: 10.1039/c1ob05260h

Cite this paper

@article{Weiss2011NovelOP, title={Novel one-pot process for the synthesis of 1,3-thiazoles via organocatalysed epoxidation of nitro-olefins.}, author={Katharina M Weiss and Shengwei Wei and Svetlana B Tsogoeva}, journal={Organic & biomolecular chemistry}, year={2011}, volume={9 9}, pages={3457-61} }